Selected Research Publications


 

Tasoulas J, Schrank TP, Bharambe H, Mehta JH, Johnson S, Divaris K, Hackman TG, Sheth S, Kirtane K, Hernandez-Prera JC, Chung CH, Yarbrough WG, Ferrarotto R, Issaeva N, Theocharis S, Amelio AL. Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites. Sci Rep. 2024;14(1):15821. Published 2024 Jul 9. doi:10.1038/s41598-024-66709-3.

Whately KM, Sengottuvel N, Edatt L, Srivastava S, Woods AT, Tsai YS, Porrello A, Zimmerman MP, Chack AC, Jefferys SR, Yacovone G, Kim DJ, Dudley AC, Amelio AL, Pecot CV. Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling. JCI Insight. 2024 May 8;9(9):e168792. doi: 10.1172/jci.insight.168792. PMID: 38716730; PMCID: PMC11141919.

Dickey BL, Putney RM, Schell MJ, Berglund AE, Amelio AL, Caudell JJ, Chung CH, Giuliano AR. Identification of a Biomarker Panel from Genome-Wide Methylation to Detect Early HPV-Associated Oropharyngeal Cancer. Cancer Prev Res (Phila). 2024 Apr 2;17(4):169-176. doi: 10.1158/1940-6207.CAPR-23-0317. PMID: 38286404; PMCID: PMC10987272.

Tasoulas J, Farquhar DR, Sheth S, Hackman T, Yarbrough WG, Agala CB, Koric A, Giraldi L, Fabianova E, Lissowska J, Świątkowska B, Vilensky M, Wünsch-Filho V, de Carvalho MB, López RVM, Holcátová I, Serraino D, Polesel J, Canova C, Richiardi L, Zevallos JP, Ness A, Pring M, Thomas SJ, Dudding T, Lee YA, Hashibe M, Boffetta P, Olshan AF, Divaris K, Amelio AL. Poor oral health influences head and neck cancer patient survival: an International Head and Neck Cancer Epidemiology Consortium pooled analysis. J Natl Cancer Inst. 2024 Jan 10;116(1):105-114. doi: 10.1093/jnci/djad156. PMID: 37725515; PMCID: PMC10777670.

Tasoulas J, Srivastava S, Xu X, Tarasova V, Maniakas A, Karreth FA, Amelio AL. Genetically engineered mouse models of head and neck cancers. Oncogene. 2023 Aug;42(35):2593-2609. doi: 10.1038/s41388-023-02783-7. Epub 2023 Jul 20. PMID: 37474617; PMCID: PMC10457205.

Murphy RM, Tasoulas J, Porrello A, Carper MB, Tsai YH, Coffey AR, Kumar S, Zeng PY, Schrank TP, Midkiff BR, Cohen S, Salazar AH, Hayward MC, Hayes DN, Olshan A, Gupta GP, Nichols AC, Yarbrough WG, Pecot CV, Amelio AL. Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer. Cancer Res Commun. 2022 Sep;2(9):987-1004. doi: 10.1158/2767-9764.crc-21-0135. Epub 2022 Sep 15. PMID: 36148399; PMCID: PMC9491693.

Terajima M, Taga Y, Nakamura T, Guo HF, Kayashima Y, Maeda-Smithies N, Parag-Sharma K, Kim JS, Amelio AL, Mizuno K, Kurie JM, Yamauchi M. Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes. Sci Rep. 2022 Aug 22;12(1):14256. doi: 10.1038/s41598-022-18165-0. PMID: 35995931; PMCID: PMC9395344.

Yao Z, Brennan CK, Scipioni L, Chen H, Ng KK, Tedeschi G, Parag-Sharma K, Amelio AL, Gratton E, Digman MA, Prescher JA. Multiplexed bioluminescence microscopy via phasor analysis. Nat Methods. 2022 Jul;19(7):893-898. doi: 10.1038/s41592-022-01529-9. Epub 2022 Jun 23. PMID: 35739310.

Carper MB, Goel S, Zhang AM, Damrauer JS, Cohen S, Zimmerman MP, Gentile GM, Parag-Sharma K, Murphy RM, Sato K, Nickel KP, Kimple RJ, Yarbrough WG, Amelio AL. Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer. Neoplasia. 2022 Jul;29:100799. doi: 10.1016/j.neo.2022.100799. Epub 2022 Apr 30. PMID: 35504112; PMCID: PMC9065880.

Sato KParag-Sharma K, Terajima M, Musicant AMMurphy RM, Ramsey MR, Hibi H, Yamauchi M, Amelio AL. Lysyl hydroxylase 2-induced collagen cross-link switching promotes metastasis in head and neck squamous cell carcinomas. Neoplasia. 2021;23(6):594-606. doi:10.1016/j.neo.2021.05.014.

Musicant AMParag-Sharma KGong W, Sengupta M, Chatterjee A, Henry ECTsai YH, Hayward MC, Sheth S, Betancourt R, Hackman TG, Padilla RJ, Parker JS, Giudice J, Flaveny CA, Hayes DN, Amelio AL. CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition. Cell Reports. 2021 Feb 23;34(8):108768. doi: 10.1016/j.celrep.2021.108768. PMID: 33626346; PMCID: PMC7955229.

Parag-Sharma KTasoulas JMusicant AM, do Nascimento-Filho CHV, Zhu Z, Twomey C, Liu P, Castilho RM, Amelio AL. Synergistic efficacy of combined EGFR and HDAC inhibitors overcomes tolerance to EGFR monotherapy in salivary mucoepidermoid carcinoma. Oral Oncol. 2021 Apr;115:105166. doi: 10.1016/j.oraloncology.2020.105166. Epub 2021 Feb 11. PMID: 33581505; PMCID: PMC8026571.

Tasoulas J, Divaris K, Theocharis S, Farquhar D, Shen C, Hackman T, Amelio AL. Impact of Tumor Site and Adjuvant Radiotherapy on Survival of Patients with Adenoid Cystic Carcinoma: A SEER Database Analysis. Cancers (Basel). 2021 Feb 3;13(4):589. doi: 10.3390/cancers13040589. PMID: 33546179; PMCID: PMC7913220.

Wang L, Lee DJ, Han H, Zhao L, Tsukamoto H, Kim YI, Musicant AMParag-Sharma K, Hu X, Tseng HC, Chi JT, Wang Z, Amelio AL, Ko CC. Application of bioluminescence resonance energy transfer-based cell tracking approach in bone tissue engineering. J Tissue Eng. 2021 Feb 16;12:2041731421995465. doi: 10.1177/2041731421995465. PMID: 33643604; PMCID: PMC7894599.

Parag-Sharma K, O'Banion CP, Henry ECMusicant AM, Cleveland JL, Lawrence DS, Amelio AL. Engineered BRET-Based Biologic Light Sources Enable Spatio-Temporal Control Over Diverse Optogenetic Systems. ACS Synth Biol. 2020 Jan 17;9(1):1-9. doi: 10.1021/acssynbio.9b00277. Epub 2019 Dec 17. PMID: 31834783.

Tang Y, Parag-Sharma KAmelio AL, Cao Y. A Bioluminescence Resonance Energy Transfer-Based Approach for Determining Antibody-Receptor Occupancy In Vivo. iScience. 2019;15:439-51. doi: 10.1016/j.isci.2019.05.003. PubMed PMID: 31121469.

Saito, T., K. Uzawa, M. Terajima, M. Shiiba, A.L. Amelio, H. Tanzawa, and M. Yamauchi, Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma. J. Dent. Res. 2019. p. 002203451982871. PubMed PMID: 30786814.

Tasoulas, J., L. Rodón, F.J. Kaye, M. Montminy, and A.L. Amelio, Adaptive Transcriptional Responses by CRTC Coactivators in Cancer. Trends Cancer. 2019. p. 111-127. PubMed PMID: 30755304.

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